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Multi-View Clustering of Microbiome Samples by Robust Similarity Network Fusion and Spectral Clustering

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成果类型:
期刊论文
作者:
Zhang, Yong*;Hu, Xiaohua;Jiang, Xingpeng(蒋兴鹏
通讯作者:
Zhang, Yong
作者机构:
[Jiang, Xingpeng; Hu, Xiaohua; Zhang, Yong] Cent China Normal Univ, Coll Comp Sci, Wuhan 430079, Hubei, Peoples R China.
[Hu, Xiaohua] Drexel Univ, Coll Comp & Informat, Philadelphia, PA 19104 USA.
通讯机构:
[Zhang, Yong] C
Cent China Normal Univ, Coll Comp Sci, Wuhan 430079, Hubei, Peoples R China.
语种:
英文
关键词:
Microbiome;data integration;network diffusion;spectral clustering;multi-view clustering
期刊:
IEEE/ACM Transactions on Computational Biology and Bioinformatics
ISSN:
1545-5963
年:
2017
卷:
14
期:
2
页码:
264-271
基金类别:
10.13039/100000001-NSF (Grant Number: IIP 1160960) NNS (Grant Number: IIP 1332024) 10.13039/100000001-NSF 10.13039/100000143-CCF (Grant Number: 0905291) 10.13039/501100001809-NSFC (Grant Number: 90920005) 10.13039/501100001809-NSFC (Grant Number: 61170189) 10.13039/501100001809-NSFC (Grant Number: 61532008) China National 12-5 plan (Grant Number: 2012BAK24B01) International Cooperation Project of Hubei Province (Grant Number: 2014BHE0017) 10.13039/501100005234-CCNU 10.13039/501100001459-MOE (Grant Number: CCNU15ZD003 and CCNU14A05014)
机构署名:
本校为第一且通讯机构
院系归属:
计算机学院
摘要:
Microbiome datasets are often comprised of different representations or views which provide complementary information, such as genes, functions, and taxonomic assignments. Integration of multi-view information for clustering microbiome samples could create a comprehensive view of a given microbiome study. Similarity network fusion (SNF) can efficiently integrate similarities built from each view of data into a unique network that represents the full spectrum of the underlying data. Based on this method, we develop a Robust Similarity Network Fusion (RSNF) approach which combines the strength o...

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