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Efficient synthesis of 5,6-dihydrothieno[3',2':4,5]-thieno[2,3-d]pyrimidin-4(3H)-ones via an iminophosphorane

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成果类型:
期刊论文
作者:
Chen, Yu Lu;Nie, Yi Bo;Ding, Ming Wu*
通讯作者:
Ding, Ming Wu
作者机构:
[Chen, Yu Lu; Nie, Yi Bo; Ding, Ming Wu] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
[Chen, Yu Lu] Xianning Vocat & Tech Coll, Dept Biol, Xianning 437100, Peoples R China.
通讯机构:
[Ding, Ming Wu] C
Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
5,6-Dihydrothieno[3 ',2 ':4,5]thieno[2,3-d]pyrimidin-4(3H)-one;Iminophosphorane;Aza-Wittig reaction;Carbodiimide;Isocyanate
关键词(中文):
高效合成;噻吩;嘧啶;Wittig反应;电话;中国化学会;BV公司;乙醇钠
期刊:
中国化学快报:英文版
ISSN:
1001-8417
年:
2009
卷:
20
期:
9
页码:
1055-1058
基金类别:
Acknowledgments We gratefully acknowledge financial support of this work by the National Natural Science Foundation of China (No. 20772041) and Key Project of Science and Technology of Ministry of Education of China (No. 107082).
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
5,6-Dihydrothieno[3′,2′:4,5]thieno[2,3-d]pyrimidin-4(3H)-ones 6 were synthesized in yields of 71–87% by a consecutive method, which includes aza-Wittig reaction of iminophosphorane 3 with aromatic isocynate to give carbodiimide 4 and subsequent reaction of 4 with various amines, phenols or alcohols in the presence of catalytic amount of sodium e...
摘要(中文):
5,6-Dihydrothieno[3′,2′:4,5]thieno[2,3-d]pyrimidin-4(3H)-ones 6 were synthesized in yields of 71-87%by a consecutive method,which includes aza-Wittig reaction of iminophosphorane 3 with aromatic isocynate to give carbodiimide 4 and subsequent reaction of 4 with various amines,phenols or alcohols in the presence of catalytic amount of sodium ethoxid...

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