A Mild Hyperthermia Hollow Carbon Nanozyme as Pyroptosis Inducer for Boosted Antitumor Immunity

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tao, Na;Jiao, Lei;Li, Huihuang;Deng, Liu*;Wang, Wei;...

通讯作者：

Deng, Liu;Liu, YN;Zhu, CZ

作者机构：

[Deng, Liu; Wang, Wei; Zhao, Senfeng; Chen, Limiao; Tao, Na; Liu, You-Nian; Chen, Wansong] Cent South Univ, Coll Chem & Chem Engn, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Changsha 410083, Hunan, Peoples R China.

[Zhu, Chengzhou; Jiao, Lei; Zhu, CZ] Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol &, Natl Key Lab Green Pesticide, Wuhan 430079, Hubei, Peoples R China.

[Li, Huihuang] Cent South Univ, Xiangya Hosp, Dept Orthopaed, Changsha 410083, Hunan, Peoples R China.

通讯机构：

[Deng, L; Liu, YN ; Zhu, CZ ] C

Cent South Univ, Coll Chem & Chem Engn, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Changsha 410083, Hunan, Peoples R China.

Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol &, Natl Key Lab Green Pesticide, Wuhan 430079, Hubei, Peoples R China.

语种：

英文

关键词：

nanozymes;hollow structures;mild hyperthermia;pyroptosis;antitumor immunity

期刊：

ACS Nano

ISSN：

1936-0851

年：

2023

卷：

期：

页码：

22844-22858

DOI：

10.1021/acsnano.3c07601

基金类别：

Natural Science Foundation of Hubei Province [22238013, 22178393, 22004042, 22074049]; National Natural Science Foundation of China [2019TP1001, 2020JJ3044]; Hunan Provincial Science and Technology Plan Project, China [CX20220174]; Postgraduate Scientific Research Innovation Project of Hunan Province [2021CFB518]; Natural Science Foundation of Hubei Province, China

机构署名：

本校为通讯机构

院系归属：

化学学院

摘要：

The immune checkpoint blockade (ICB) antibody immunotherapy has demonstrated clinical benefits for multiple cancers. However, the efficacy of immunotherapy in tumors is suppressed by deficient tumor immunogenicity and immunosuppressive tumor microenvironments. Pyroptosis, a form of programmed cell death, can release tumor antigens, activate effective tumor immunogenicity, and improve the efficiency of ICB, but efficient pyroptosis for tumor treatment is currently limited. Herein, we show a mild hyperthermia-enhanced pyroptosis-mediated immunotherapy based on hollow carbon nanozyme, which can s...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

A Mild Hyperthermia Hollow Carbon Nanozyme as Pyroptosis Inducer for Boosted Antitumor Immunity

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问