期刊论文、会议论文

Tian, Tianhai

英文

BMC Medical Genomics

1755-8794

2017

10

5

31-43

IEEE International Conference on Bioinformatics and Biomedicine (BIBM) - Medical Genomics

DEC 15-18, 2016

Shenzhen, PEOPLES R CHINA

[Wei, Jiangyong] Zhongnan Univ Econ & Law, Sch Stat & Math, Wuhan 430073, Hubei, Peoples R China.^[Hu, Xiaohua] Cent China Normal Univ, Sch Comp, Wuhan 430079, Hubei, Peoples R China.^[Zou, Xiufen] Wuhan Univ, Sch Math & Stat, Wuhan 430072, Hubei, Peoples R China.^[Tian, Tianhai] Monash Univ, Sch Math Sci, Melbourne, Vic 3800, Australia.

IEEE

CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND

BMC

10.1186/s12920-017-0312-z

T.T. is supported by the Australian Research Council (ARC) Discovery Projects (DP120104460) which supports the publication cost of this paper.

本校为其他机构

Background: Recent advances in omics technologies have raised great opportunities to study large-scale regulatory networks inside the cell. In addition, single-cell experiments have measured the gene and protein activities in a large number of cells under the same experimental conditions. However, a significant challenge in computational biology and bioinformatics is how to derive quantitative information from the single-cell observations and how to develop sophisticated mathematical models to describe the dynamic properties of regulatory netwo...