Visualization is an important method of data analysis in the study of microbiome, with the dimensionality reduction techniques as its prerequisites for high-dimensional data. Multidimensional scaling (MDS), as a popular method for data visualization, can provide a low-dimensional representation of the original data utilizing its distance matrix. Meanwhile, the unique fraction metric (UniFrac) is a very reasonable and biologically meaningful metric for calculating distance matrices through a phylogenetic tree constructed from microbiome data. However, due to the complexity of the phylogenetic t...
