Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China<&wdkj&>Zhongnan Hospital of Wuhan University, Wuhan 430062, P. R. China<&wdkj&>Department of Neurosurgery, Remin Hospital of Wuhan University, Wuhan 430079, P. R. China
National Natural Science Foundation [22022404, 22074050, 82172055, 81870939]; fundamental research funds for the Central Universities [CCNU22QN007]
机构署名：
本校为其他机构
院系归属：
化学学院
摘要：
Herein, we construct a series of Ru(ii) metallacycles with multimodal chemo-phototherapeutic properties, which exhibited much higher anticancer activity and better cancer-cell selectivity than cisplatin. The antitumor mechanism could be ascribed to the activation of caspase 3/7 and the resulting apoptosis. These results open new possibilities for Ru(ii) metallacycles in bi...
