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Iodine-promoted efficient synthesis of diheteroaryl thioethers via the integration of iodination/condensation/cyclization/dehydration sequences

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成果类型:
期刊论文
作者:
Xue, Wei-Jian;Li, Hong-zheng;Zheng, Kai-lu;Wu, An-xin*吴安心
通讯作者:
Wu, An-xin(吴安心
作者机构:
[Wu, An-xin; Xue, Wei-Jian; Li, Hong-zheng; Zheng, Kai-lu] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构:
[Wu, An-xin] C
Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
I-2-promoted;Diheteroaryl thioethers;Free of foul-smell thiols;Free of transition metal;Thiourea
期刊:
Tetrahedron Letters
ISSN:
0040-4039
年:
2014
卷:
55
期:
40
页码:
5544-5547
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21032001, 21272085]; Central China Normal University [2013YBYB53]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
A novel method for the construction of diheteroaryl thioethers from aromatic methyl ketones and thiourea is described. Iodine is the unique catalyst in this protocol. The transformation is free of foul-smell thiols and transition metal. In addition, this method could synthesize two thiazole rings and a sulfur bridge in one pot. (C)...

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