Jiangnan Area in the Qing Dynasty had experienced at least 145 Years of Epidemic Dis- aster, with an average epidemic frequency of 54.10%. In all Years of Epidemic Disaster, 57.20% oc- curred in the Kingdoms of Kangxi (1662--1722), Qianlong (1736--1795) and Guangxu (1875-- 1908). In seasonal level, the prevalence of epidemic disasters seemed more preferable in summer and autumn, in which occurred about 74.60% epidemic accidents and spread most extensive epidemic are- as. By the statistic analysis on Epidemic Index of Decade and Epidemic C...