期刊论文

Wu, An-xin

英文

Organic Letters

1523-7060

2017

19

12

3319-3322

10.1021/acs.orglett.7b01492

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21472056, 21602070]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [CCNU15ZX002, CCNU16A05002]; 111 ProjectMinistry of Education, China - 111 Project [B17019]

本校为第一且通讯机构

A novel iodine-promoted oxidative cross-coupling/cyclization of 2-(pyridin-2-yl)acetate derivatives and methyl ketones via the cleavage of multiple Csp3–H bonds has been developed, which also achieved efficient cleavage of a C–C bond in the 2-(pyridin-2-yl)acetate derivatives. This protocol represents an elegant molecular fragment assembly of diverse 3-(pyridin-2-yl)indolizines via a formal [3 + 1 + 1] annulation. Notably, the pyridine derivatives serve two pivotal roles to provide two fragments to construct 3-(pyridin-2-yl)indolizine sk...