A fluorescent turn-on H2S-responsive probe: design, synthesis and application

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成果类型：

期刊论文

作者：

Zhang, Yufeng;Chen, Haiyan*;Chen, Dan;Wu, Di;Chen, Xiaoqiang;...

通讯作者：

Chen, Haiyan

作者机构：

[Zhang, Yufeng; Liu, Sheng Hua; Yin, Jun; Wu, Di] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.

[Chen, Haiyan; Chen, Dan] China Pharmaceut Univ, Sch Engn, Dept Biomed Engn, Nanjing 210009, Jiangsu, Peoples R China.

[Chen, Xiaoqiang] Nanjing Tech Univ, Coll Chem & Chem Engn, State Key Lab Mat Oriented Chem Engn, Nanjing 210009, Jiangsu, Peoples R China.

[Chen, Haiyan] China Pharmaceut Univ, Sch Engn, Dept Biomed Engn, 24 Tongjia Lane, Nanjing 210009, Jiangsu, Peoples R China.

通讯机构：

[Chen, Haiyan] C

China Pharmaceut Univ, Sch Engn, Dept Biomed Engn, 24 Tongjia Lane, Nanjing 210009, Jiangsu, Peoples R China.

语种：

英文

期刊：

Organic & Biomolecular Chemistry

ISSN：

1477-0520

年：

2015

卷：

期：

页码：

9760-9766

DOI：

10.1039/c5ob01305d

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21272088, 21472059, 21402057, 81371684]; Scientific Research Foundation for the Returned Overseas Chinese Scholars, Ministry of EducationScientific Research Foundation for the Returned Overseas Chinese Scholars; CCNU from the colleges' basic research and operation of MOEMinistry of Education, Singapore [CCNU14A05009, CCNU14F01003]

机构署名：

本校为第一机构

院系归属：

化学学院

摘要：

Hydrogen sulfide (H2S) is considered as the third signaling molecule in vivo and it plays an important role in various physiological processes and pathological processes in vivo, such as vasodilation, apoptosis, neurotransmission, ischemia/reperfusion-induced injury, insulin secretion and inflammation. Developing a highly selective and sensitive method that can detect H2S in the biological system is very important. In this work, a colorimetric and “turn-on” fluorescent probe is developed. Furthermore, this probe displays a highly selective re...

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A fluorescent turn-on H2S-responsive probe: design, synthesis and application

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