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Sorting Nexin1 negatively modulates phosphate uptake by facilitating Phosphate Transporter1;1 degradation in Arabidopsis

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成果类型:
期刊论文
作者:
Zhang, Yu;Wang, Lin-Feng;Han, Shu-Yue;Ren, Feng;Liu, Wen-Cheng
通讯作者:
Liu, WC;Ren, F
作者机构:
[Liu, Wen-Cheng; Zhang, Yu; Wang, Lin-Feng; Han, Shu-Yue] Henan Univ, Sch Life Sci, State Key Lab Crop Stress Adaptat & Improvement, Kaifeng 475004, Peoples R China.
[Ren, Feng] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
通讯机构:
[Liu, WC ] H
[Ren, F ] C
Henan Univ, Sch Life Sci, State Key Lab Crop Stress Adaptat & Improvement, Kaifeng 475004, Peoples R China.
Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
SNX1;PHT1;phosphate;protein stability;plasma membrane localization
期刊:
PLANT JOURNAL
ISSN:
0960-7412
年:
2022
卷:
111
期:
1
页码:
72-84
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [32000150, 31971814]; Natural Science Foundation of Henan Province [222300420401]
机构署名:
本校为通讯机构
院系归属:
生命科学学院
摘要:
High-affinity phosphate (Pi) transporters (PHTs) PHT1;1 and PHT1;4 are necessary for plant root Pi uptake especially under Pi-deficient conditions, but how their protein stability is modulated remains elusive. Here, we identified a Ttransfer DNA insertion mutant of Sorting Nexin1 (SNX1), which had more Pi content and less anthocyanin accumulation than the wild type under deficient Pi. By contrast, the snx1-2 mutant displayed higher sensitivity to exogenous arsenate in terms of seed germination and root elongation, revealing higher Pi uptake rates. Further study showed that SNX1 could co-locali...

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