期刊论文

Ma, P

英文

Ecotoxicology and Environmental Safety

0147-6513

2023

256

114848

10.1016/j.ecoenv.2023.114848

This work was supported by the National Natural Science Foundation of China ( 42177416 ) and Health Commission of Hubei Province Scientific Research Project ( WJ2021Z006 ).

本校为其他机构

Dibutyl phthalate (DBP), used as a plasticizer, is of wide concern as an environmental pollutant since it has certain immunotoxicity. Although there is growing evidence supporting a link between DBP exposure and allergic airway inflammation, there is less information concerned with whether the ferroptosis pathway is involved in DBP-aggravated allergic asthma in ovalbumin (OVA)-sensitized mice. This study aimed to investigate the role and underlying mechanisms of ferroptosis in DBP-exposed allergic asthmatic mice. Balb/c mice were orally exposed to 40mg/kg(-1) DBP for 28 days, followed by sensi...