版权说明 操作指南
首页 > 成果 > 详情

DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Deng, Xuefeng;Xu, Peng;Zou, Wei;Shen, Weiran;Peng, Jianxin;...
通讯作者:
Qiu, Jianming
作者机构:
[Xu, Peng; Shen, Weiran; Qiu, Jianming; Zou, Wei; Deng, Xuefeng] Univ Kansas, Med Ctr, Dept Microbiol Mol Genet & Immunol, Kansas City, KS 66103 USA.
[Xu, Peng; Liu, Kaiyu; Peng, Jianxin] Cent China Normal Univ, Coll Life Sci, Wuhan, Peoples R China.
[Engelhardt, John F.; Yan, Ziying] Univ Iowa, Dept Anat & Cell Biol, Iowa City, IA USA.
通讯机构:
[Qiu, Jianming] U
Univ Kansas, Med Ctr, Dept Microbiol Mol Genet & Immunol, Kansas City, KS 66103 USA.
语种:
英文
关键词:
DNA damage;DNA replication;parvovirus
期刊:
Journal of Virology
ISSN:
0022-538X
年:
2017
卷:
91
期:
1
页码:
JVI.01831-16
基金类别:
PHS from NIAID, NIH [AI070723, AI105543, AI112803]; COBRE program of NIGMS, NIH [P30 GM103326]; Cystic Fibrosis Foundation [YAN15XX0]; NATIONAL HEART, LUNG, AND BLOOD INSTITUTEUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Heart Lung & Blood Institute (NHLBI) [P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670, P01HL051670] Funding Source: NIH RePORTER; NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute of Allergy & Infectious Diseases (NIAID) [R01AI070723, R01AI070723, R21AI112803, R01AI070723, R01AI070723, R01AI070723, R01AI070723, R56AI070723, R01AI070723, R21AI105543, R01AI070723, R01AI070723, R21AI112803, R01AI070723, R21AI105543] Funding Source: NIH RePORTER; NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) [P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759, P30DK054759] Funding Source: NIH RePORTER; NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute of General Medical Sciences (NIGMS) [P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326, P30GM103326] Funding Source: NIH RePORTER
机构署名:
本校为其他机构
院系归属:
生命科学学院
摘要:
Human bocavirus 1 (HBoV1), an emerging human-pathogenic respiratory virus, is a member of the genus Bocaparvovirus of the Parvoviridae family. In human airway epithelium air-liquid interface (HAE-ALI) cultures, HBoV1 infection initiates a DNA damage response (DDR), activating all three phosphatidylinositol 3-kinase-related kinases (PI3KKs): ATM, ATR, and DNA-PKcs. In this context, activation of PI3KKs is a requirement for amplification of the HBoV1 genome (X. Deng, Z. Yan, F. Cheng, J. F. Engelhardt, and J. Qiu, PLoS Pathog, 12:e1005399, 2016, https://doi.org/10.1371/journal.ppat.1005399), and...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com