In the crystal structure of the title compound, C21H15FN4O2, the two fused rings of pyrrolo[3,2-d]pyrimidine form a dihedral angle of 2.91 (12)°. The fluorophenyl and phenyl rings are twisted with respect to the heterocyclic pyrrolo[3,2-d]pyrimidine system, making dihedral angles of 75.23 (12) and 46.11 (14)°, respectively. The crystal packing is mainly stabilized by C - H⋯O and C - H⋯F hydrogen bonds, and π-π inter-actions with inter-planar distances of 3.315 (1) Å between adjacent pyrrole ring centroids and 3.300 (1) Å between pyrrole...