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Synthesis of iminoisoindolinones via a cascade of the three-component Ugi reaction, palladium catalyzed isocyanide insertion, hydroxylation and an unexpected rearrangement reaction

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成果类型:
期刊论文
作者:
Ren, Zhi-Lin;He, Ping;Lu, Wen-Ting;Sun, Mei;Ding, Ming-Wu*
通讯作者:
Ding, Ming-Wu
作者机构:
[Lu, Wen-Ting; Sun, Mei; Ding, Ming-Wu; He, Ping; Ren, Zhi-Lin] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Hubei Int Sci & Technol Cooperat Base Pesticide &, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Ding, Ming-Wu] C
Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Hubei Int Sci & Technol Cooperat Base Pesticide &, Wuhan 430079, Hubei, Peoples R China.
语种:
英文
期刊:
Organic & Biomolecular Chemistry
ISSN:
1477-0520
年:
2018
卷:
16
期:
34
页码:
6322-6331
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21572075]; 111 ProjectMinistry of Education, China - 111 Project [B17019]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
A robust ligand-free palladium-catalyzed cascade reaction for the synthesis of diversely substituted iminoisoindolinones has been developed. The cascade reaction involves isocyanide insertion into Ugi-3CR adducts, accompanied by unexpected hy...

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