SexuallyTransmitted Diseases(STD)is a kind of transmitted disease which is seriouslyharmful to human health. This paper, using the variation coefficient, the convergence test method and quantile regression, focused on the spatio-temporal characteristics and economic driving mechanism of gonorrhea and syphilis epidemic in China, 2004-2014.The results showed that: 1) The patient number of gonorrhea had decreased, but syphilis patients increased since 2004, the relative proportion was transformed, and the overall patient number continuously increa...