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Rising interest in the accurate and controllable anticancer strategy: Based on photon-evoked pyroptosis engineering perspective

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成果类型:
期刊论文
作者:
Zhang, Xiangqian;Zhang, Tuotuo;Tuo, Wei;Liu, Yanping;Umar, Talha;...
通讯作者:
Li, XY;Deng, GZ;Sun, Y
作者机构:
[Zhang, Xiangqian; Li, XY; Wu, Zilin; Li, Xiangyang] Guizhou Univ, Natl Key Lab Green Pesticides, Key Lab Green Pesticide & Agr Bioengn, Minist Educ, Guiyang 550025, Peoples R China.
[Zhang, Xiangqian; Chen, Yu; Deng, GZ; Umar, Talha; Deng, Ganzhen; Zhou, Qingqing] Huazhong Agr Univ, Coll Anim Sci & Vet Med, Natl Key Lab Agr Microbiol, Wuhan 430070, Peoples R China.
[Sun, Y; Sun, Yao; Zhang, Tuotuo] Cent China Normal Univ, Coll Chem, Natl Key Lab Green Pesticides, Wuhan 430079, Peoples R China.
[Tuo, Wei] Jiangsu Inst Nucl Med, NHC Key Lab Nucl Med, Jiangsu Key Lab Mol Nucl Med, Wuxi 214063, Peoples R China.
[Liu, Yanping] Wuhan Univ, Dept Neurol, Zhongnan Hosp, Wuhan 430071, Peoples R China.
通讯机构:
[Sun, Y ] C
[Li, XY ] G
[Deng, GZ ] H
Guizhou Univ, Natl Key Lab Green Pesticides, Key Lab Green Pesticide & Agr Bioengn, Minist Educ, Guiyang 550025, Peoples R China.
Huazhong Agr Univ, Coll Anim Sci & Vet Med, Natl Key Lab Agr Microbiol, Wuhan 430070, Peoples R China.
语种:
英文
关键词:
Photon-evoked pyroptosis;Precise spatiotemporal control;Photon-evoked strategies;Pyroptosis pathway
期刊:
Coordination Chemistry Reviews
ISSN:
0010-8545
年:
2024
卷:
501
页码:
215588
基金类别:
National Key Research and Development Program [2021YFA0716702]; National Natural Science Foundation of China [22022404, 22074050, 22374055, 32172416]; National Natural Science Foundation of Hubei Province (China) [2022CFA033]; Fundamental Research Funds for the Central Universities [CCNU22QN007]; Medical Sci-Tech innovation platform of Zhongnan Hospital, Wuhan University [PTXM2023023]; Open Program of NHC Key Laboratory of Nuclear Medicine and Jiangsu Key Laboratory of Molecular Nuclear Medicine [KF202211]; Talents of Guizhou Science and Technology Cooperation Platform [20215623]
机构署名:
本校为通讯机构
院系归属:
化学学院
摘要:
Pyroptosis has garnered significant interest due to its involvement in cancer progression and potential to trigger inflammation and host immune responses. While many efforts have been made to induce pyroptosis using chemotherapeutic agents, these approaches often result in off-target effects, drug resistance, and unwanted systemic toxicity. Furthermore, the non-specific activation of pyroptosis could lead to pro-inflammatory death, creating a microenvironment that potentially heightens the chances of cancer proliferation and metastasis. To solve these limitations, photon-evoking pyroptosis eng...

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