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New Efficient Synthesis of 2,3,5-Trisubstituted Pyrimidin-4(3H)-ones from Baylis-Hillman Adducts

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成果类型:
期刊论文
作者:
Zhong, Ying*;Wu, Lei;Ding, Ming-Wu
通讯作者:
Zhong, Ying
作者机构:
[Zhong, Ying; Ding, Ming-Wu; Wu, Lei] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
通讯机构:
[Zhong, Ying] C
Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
azides;heterocycles;cyclizations;Wittig reactions;amines;alcohols;phenols
期刊:
SYNTHESIS-STUTTGART
ISSN:
0039-7881
年:
2012
卷:
44
期:
19
页码:
3085-3089
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21032001, 21172085]; CCNU from the college's basic research and operation of MOEMinistry of Education, Singapore [CCNU11C01002]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
Azides obtained from Baylis–Hillman adducts were treated with triphenylphosphine to give the corresponding iminophosphoranes that underwent aza-Wittig reactions with aryl isocyanates and then reacted with amines, alcohol, or phenols in the presence of catalytic amounts of sodium alkoxide or potassium carbonate to give the corresponding 2,3,5-trisubstitu...

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