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Chiral Selective Adhesion of Protein Droplets on Calix[4]arene-Enantiomer-Modified Surfaces

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成果类型:
期刊论文
作者:
Mei, Yuxiao;Quan, Jiaxin;Gu, Yulin;Yang, Yuxia;Huang, Jinmei;...
通讯作者:
Sun, Kunpeng(sunkp@licp.cas.cn)
作者机构:
[Mei, Yuxiao; Quan, Jiaxin; Gu, Yulin; Yang, Yuxia; Sun, Kunpeng] National Engineering Research Center for Fine Petrochemical Intermediates, Lanzhou Institute of Chemical Physics, Chinese Academic Sciences, Lanzhou
730000, China
[Huang, Jinmei; Li, Haibing] Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan
430079, China
[Mei, Yuxiao; Quan, Jiaxin] 730000, China<&wdkj&>Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan
通讯机构:
[Kunpeng Sun] N
[Haibing Li] K
Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, 430079, P. R. China<&wdkj&>National Engineering Research Center for Fine Petrochemical Intermediates, Lanzhou Institute of Chemical Physics, Chinese Academic Sciences, Lanzhou, 730000, P. R. China
语种:
英文
关键词:
BSA-adhesion;calix[4]arene;chiral surface;enantio-selectivity;signal transduction
期刊:
ACS Applied Bio Materials
ISSN:
2576-6422
年:
2020
卷:
3
期:
2
页码:
1226-1232
基金类别:
This work was financially supported by the National Key Research and Development Program of China (2018YFD0200102), the National Natural Science Foundation of China (21772055, 21572076, 21911530178), the Nature Science Foundation of Hubei Province (2018CFB534), the 111 Project (B17019) and self-determined research funds of CCNU from the colleges’ basic research and operation of MOE, the Fundamental Research Funds for the Central Universities (Excellent Doctor Training Program).
机构署名:
本校为其他机构
院系归属:
化学学院
摘要:
Chiral-specific assembly is involved in many biochemical processes, such as DNA hybridization, protein adhesion, and sugar recognition. However, the signals of chiral interaction are usually very weak, and it is difficult to investigate the enantioselective behaviors. Therefore, it is necessary to construct the functional materials to regulate the selective behaviors of protein droplets via weak chiral interaction, which is also significant for the biological process of protein adhesive behaviors and proteinic drug delivery. Here, S- and R-amin...

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