National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21272085, 21472056]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
A highly efficient molecular iodine catalyzed oxidative amidation of aryl methyl ketones with formamidine hydrochloride has been developed. This reaction represents a novel strategy for the synthesis of free (N-H) alpha-ketoamides. Based on the experimental results, a self-sequenced iodination/Kornblum oxidation/amidation/oxidation...