This work was supported by the Hubei Province Health and Family Planning Scientific Research Project ( WJ2017Z027 ), the Hubei Province College Outstanding Young and Middle-aged Innovative Research Team Project ( T201717 ), and the Science and Technology Research Project of Hubei Provincial Department of Education ( B2018172 ).
机构署名：
本校为其他机构
院系归属：
城市与环境科学学院
摘要：
Diisodecyl phthalate (DIDP) is a new type of phthalate used in the coating of pharmaceutical pills and in plastic food wrappers. This research was conducted to investigate whether DIDP could cause learning and memory impairment in mice, using formaldehyde (FA) to construct a positive control. Behavioral analysis showed that oral administration of 15 mg kg −1 ·d −1 DIDP combined with inhalation of 1 mg m −3 FA led to learning and memory impairment in mice. Histopathological observations of the brain showed that the pathological alterations i...
