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Experimental and simulation study on shear stress-induced erythrocyte damage based on vortex oscillator Response to reviewers:

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成果类型:
期刊论文
作者:
Xu Mei*;Li-Pu Zhao;Lian Hou;Ying-Ying Zhong
通讯作者:
Xu Mei
作者机构:
State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
[Li-Pu Zhao; Lian Hou] School of Mechanical and Electrical Engineering, Silicon Lake Vocational and Technical College, Suzhou 215006, China.
[Ying-Ying Zhong] College of Education, Central China Normal University, Wuhan 430079, China.
[Xu Mei] State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.<&wdkj&>School of Mechanical and Electrical Engineering, Silicon Lake Vocational and Technical College, Suzhou 215006, China.
通讯机构:
[Xu Mei] S
State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.<&wdkj&>School of Mechanical and Electrical Engineering, Silicon Lake Vocational and Technical College, Suzhou 215006, China.
语种:
英文
关键词:
CFD;Hemolysis prediction model;Vortex oscillator;Shear stress
期刊:
Biomedical Engineering Communications
年:
2024
卷:
3
期:
1
页码:
5
机构署名:
本校为其他机构
院系归属:
教育学院
摘要:
Background: Shear stress-induced erythrocyte damage, namely hemolysis, is an important problem in the development of blood-contacting medical devices such as mechanical circulatory support (MCS) devices. Computational fluid dynamics (CFD) simulation combined with hemolysis prediction models have been widely used to predict hemolysis. With the development of hemolysis prediction models, the new hemolysis prediction model requires more experimental data to verify. In addition, the difference of in vitro blood-shearing device also affect the accuracy of hemolysis prediction. Methods: To address t...

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