IEEE Engn Med & Biol Soc, Sichuan Univ, Wuhan Univ
出版地：
345 E 47TH ST, NEW YORK, NY 10017 USA
出版者：
IEEE
ISBN：
978-1-4244-4713-8
基金类别：
Open Project of Hubei Key Laboratory of Genetic Regulation and Integrative Biology
机构署名：
本校为第一且通讯机构
院系归属：
生命科学学院
摘要：
In order to explore distant-site genotoxic effect of gaseous formaldehyde on genetic material of marrow cells in mice. SPF-class Kun Ming male mice were exposed to gaseous formaldehyde for 72 hours in such concentration as 0.5mg/m(3), 1.0mg/m(3) and 3.0mg/m(3). We applied the random amplified polymorphic DNA (RAPD) method to evaluate the genotoxic effect of the gaseous formaldehyde. The results of the RAPD profiles showed obvious differences between normal and exposed groups. The number of the varied bands increased gradually with the concentration of gaseous formaldehyde. Genomic template sta...
