Starting from diethyl 2- （ ethoxymethylene ） malonate, the target molecules ethyl 4-hydroxypyrimidine-5-earboxylate and ethyl 4-hydroxy-2-methylpyrimidine-5-carboxylate were synthesized at a yield of 80% and 92%, respectively. The one-step method for synthesis of the target molecules was simple with a higher yield of target produc...
