期刊论文

Zhu, Manlu;Dai, Xiongfeng

英文

mSphere

2379-5042

2018

3

2

10.1128/mSphere.00095-18

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31700039, 31700089]; startup funding from the Central China Normal University; Institute of Science and Technology Development of the Central China Normal University; NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute of General Medical Sciences (NIGMS) [R01GM095903, R01GM095903, R01GM095903, R01GM095903, R01GM095903, R01GM095903, R01GM095903, R01GM095903, R01GM095903, R01GM095903] Funding Source: NIH RePORTER

本校为第一且通讯机构

Environmental stresses often co-occur when bacteria encounter antibiotic treatment inside the human body. The cellular response to environmental stressors can alter the global gene expression pattern of bacteria. However, the relationship between the cellular stress response and antibiotic susceptibility remains poorly understood. Here we studied the effect of high salt, an important environmental stress condition inside the human body, on bacterial susceptibility to antibiotics. We found that high salt reduces the susceptibility of Escherichia...