期刊论文

Dai, Dao-Qing

英文

BMC Bioinformatics

1471-2105

2014

15

1

1-14

10.1186/1471-2105-15-335

National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [11171354, 61375033, 61402190]; Ministry of Education of ChinaMinistry of Education, China [20120171110016]; Natural Science Foundation of Guangdong ProvinceNational Natural Science Foundation of Guangdong Province [S2013020012796]; International Program Fund of 985 Project, Sun Yat-sen University

本校为其他机构

Background: Proteins dynamically interact with each other to perform their biological functions. The dynamic operations of protein interaction networks (PPI) are also reflected in the dynamic formations of protein complexes. Existing protein complex detection algorithms usually overlook the inherent temporal nature of protein interactions within PPI networks. Systematically analyzing the temporal protein complexes can not only improve the accuracy of protein complex detection, but also strengthen our biological knowledge on the dynamic protein ...