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Identifying protein complexes via multi-network clustering

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成果类型:
期刊论文、会议论文
作者:
Le Ou-Yang;Yan, Hong;Zhang, Xiao-Fei*
通讯作者:
Zhang, Xiao-Fei
作者机构:
[Le Ou-Yang] Shenzhen Univ, Coll Informat Engn, Shenzhen 518060, Peoples R China.
[Le Ou-Yang; Yan, Hong] City Univ Hong Kong, Dept Elect & Engn, Hong Kong, Hong Kong, Peoples R China.
[Zhang, Xiao-Fei] Cent China Normal Univ, Sch Math & Stat, Wuhan 430079, Peoples R China.
[Zhang, Xiao-Fei] Cent China Normal Univ, Hubei Key Lab Math Sci, Wuhan 430079, Peoples R China.
通讯机构:
[Zhang, Xiao-Fei] C
Cent China Normal Univ, Sch Math & Stat, Wuhan 430079, Peoples R China.
Cent China Normal Univ, Hubei Key Lab Math Sci, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Domain-domain interaction;Multi-network clustering;Protein complex;Protein-protein interaction
期刊:
2016 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM)
ISSN:
2156-1125
年:
2017
页码:
645-650
会议名称:
IEEE International Conference on Bioinformatics and Biomedicine (IEEE BIBM)
会议论文集名称:
IEEE International Conference on Bioinformatics and Biomedicine-BIBM
会议时间:
DEC 15-18, 2016
会议地点:
Shenzhen, PEOPLES R CHINA
会议主办单位:
[Le Ou-Yang] Shenzhen Univ, Coll Informat Engn, Shenzhen 518060, Peoples R China.^[Le Ou-Yang;Yan, Hong] City Univ Hong Kong, Dept Elect & Engn, Hong Kong, Hong Kong, Peoples R China.^[Zhang, Xiao-Fei] Cent China Normal Univ, Sch Math & Stat, Wuhan 430079, Peoples R China.^[Zhang, Xiao-Fei] Cent China Normal Univ, Hubei Key Lab Math Sci, Wuhan 430079, Peoples R China.
会议赞助商:
IEEE, IEEE Comp Soc, Natl Sci Fdn, Harbin Inst Technol
主编:
Tian, T Jiang, Q Liu, Y Burrage, K Song, J Wang, Y Hu, X Morishita, S Zhu, Q Wang, G
出版地:
10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1264 USA
出版者:
IEEE COMPUTER SOC
ISBN:
978-1-5090-1610-5
基金类别:
National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [61402190, 61532008, 61602309]; Self-determined Research Funds of CCNU from the colleges' basic research and operation of MOE [CCNU15A05039, CCNU15ZD011]; Hong Kong Research Grants CouncilHong Kong Research Grants Council [CityU C1007-15G]
机构署名:
本校为通讯机构
院系归属:
数学与统计学学院
摘要:
The detection of protein complexes from protein-protein interaction (PPI) networks is an important step toward understanding the functional organization within cells. A great number of graph clustering algorithms have been proposed to undertake this task. Since PPI data collected by high-throughput technologies is quite noisy, simply applying graph clustering algorithms on PPI data is generally not adequate to achieve reliable prediction results. Behind protein interactions, there are protein domains that interact with each other. Jointly explo...

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