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Toxic effect of cooking oil fume (COF) on lungs: Evidence of endoplasmic reticulum stress in rat

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成果类型:
期刊论文
作者:
Deng, Linjing;Ma, Yongsheng;Ma, Ping;Wu, Yang;Yang, Xu;...
通讯作者:
Linjing Deng<&wdkj&>Qihong Deng
作者机构:
[Deng, Linjing] Jiangxi Univ Finance & Econ, Sch Tourism & Ubran Management, Nanchang 330000, Jiangxi, Peoples R China.
[Ma, Yongsheng] CDC Jinan, Jinan 250000, Peoples R China.
[Wu, Yang; Ma, Ping] Hubei Univ Sci & Technol, Sch Publ Hlth, Xianning 437100, Peoples R China.
[Yang, Xu] Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430070, Peoples R China.
[Deng, Qihong] Zhengzhou Univ, Sch Publ Hlth, Zhengzhou 450001, Peoples R China.
通讯机构:
[Linjing Deng] s
[Qihong Deng] S
School of Public Health, Zhengzhou University, Zhengzhou 450001, China<&wdkj&>school of tourism and ubran management, Jiangxi University of Finance and Economics, Nanchang 330000, China
语种:
英文
关键词:
Cooking oil fumes;Oxidative stress;Endoplasmic reticulum stress;Apoptosis
期刊:
Ecotoxicology and Environmental Safety
ISSN:
0147-6513
年:
2021
卷:
221
页码:
112463
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41977369, 21777193]
机构署名:
本校为其他机构
院系归属:
生命科学学院
摘要:
Background: Cooking oil fumes (COF) is one of the primary sources of indoor air pollution in China, which is associated with respiratory diseases such as acute lung injury and lung cancer. However, evidence of COF toxic effect was few. Objectives: The research was aimed to investigate the toxic effect and the underlying mechanisms induced by COF. Methods: The female Wistar rats were randomly divided into several groups, including control group, COF exposure group and VE protection group, and instilled intratracheally with different COF suspensi...

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