Epidemic disaster,a top disaster of human society, results from the massive prevalence of acute infectious diseases, and threatens directly human health safety and life security. From 770BC through AD1911, Hubei province experienced at least 136 years of epidemic prevalence,the temporal change of its epidemic frequency in the historical period showed a longterm increasing tendency, including 2 peaks of epidemic frequency of the 15 th~19 th century and the 3 rd~5 th century, this result probably was closely related with the tendency of both co...