期刊论文

中文

华中师范大学学报(自然科学版)

1000-1190

2008

42

1

62-64

10.19603/j.cnki.1000-1190.2008.01.016

湖北省自然科学基金资助项目（2007ABA001）； 湖北省教育厅优秀中青年人才项目（Q200729001）；

本校为其他机构

为了寻找高生物活性的脲类化合物，通过2-氨基-5-（3-吡啶基）-1．3，4-噻二唑与酰基叠氮化物反应，设计合成了7个新的N-[5-（3-吡啶基）-1，3，4-噻二唑-2-基]-N。取代苯基脲，其中芳酰基替氮化物足以芳酸、氯甲酸乙酯、卺氮化钠为起始原料采用“一锅法”所制得．目标化合物的结构经红外光谱、核磁共振氢淆和元素分析了以确证．初步的生物活性测定表明，部分目标化合物具有良好的植物生长调节活性．

In order to find biologically active urea compounds, seven new N-[5-（3 pyridyl）-l, 3,4-thiadiazol 2-yl] N-（substituted phenyl）urea derivatives were synthesized by the reaction of 2-amino 5 （3 pyridyl）-l, 3,4 thiadiazole with aroylazides, which were prepared starting from carboxylic acids, ethyl chloroformate and sodium azide by one-pot procedure. Their structures were confirmed by IR, 1H NMR spectroscopy and elementary analysis. The preliminary bio- logical activity tests showed that some of the title...