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A novel dimensionality reduction algorithm based on Laplace matrix for microbiome data analysis

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成果类型:
期刊论文、会议论文
作者:
Fan, Yetian*;Jiang, Xingpeng(蒋兴鹏);Hu, Xiaohua;Song, Bo;Ling, Yuan;...
通讯作者:
Fan, Yetian
作者机构:
[Fan, Yetian; Wu, Wei] Dalian Univ Technol, Sch Math Sci, Dalian 116023, Peoples R China.
[Jiang, Xingpeng] Cent China Normal Univ, Sch Comp Sci, Wuhan 430079, Peoples R China.
[Hu, Xiaohua; Ling, Yuan; Song, Bo] Drexel Univ, Coll Comp & Informat, Philadelphia, PA 19104 USA.
通讯机构:
[Fan, Yetian] D
Dalian Univ Technol, Sch Math Sci, Dalian 116023, Peoples R China.
语种:
英文
关键词:
Dimensionality reduction;Metagenomics;Unifrac;Visulaization
期刊:
PROCEEDINGS 2015 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE
ISSN:
2156-1125
年:
2015
页码:
49-54
会议名称:
IEEE International Conference on Bioinformatics and Biomedicine - Medical Informatics and Decision Making
会议论文集名称:
IEEE International Conference on Bioinformatics and Biomedicine-BIBM
会议时间:
NOV 09-12, 2015
会议地点:
Washington, DC
会议主办单位:
[Fan, Yetian;Wu, Wei] Dalian Univ Technol, Sch Math Sci, Dalian 116023, Peoples R China.^[Jiang, Xingpeng] Cent China Normal Univ, Sch Comp Sci, Wuhan 430079, Peoples R China.^[Hu, Xiaohua;Song, Bo;Ling, Yuan] Drexel Univ, Coll Comp & Informat, Philadelphia, PA 19104 USA.
会议赞助商:
IEEE, IEEE Comp Soc, Natl Sci Fdn
主编:
Huan, J Miyano, S Shehu, A Hu, X Ma, B Rajasekaran, S Gombar, VK Schapranow, IM Yoo, IH Zhou, JY Chen, B Pai, V Pierce, B
出版地:
345 E 47TH ST, NEW YORK, NY 10017 USA
出版者:
IEEE
ISBN:
978-1-4673-6798-1
机构署名:
本校为其他机构
院系归属:
计算机学院
摘要:
Visualization is an important method in microbiome data analysis, and dimensionality reduction is a necessary procedure to achieve it. Multidimensional Scaling (MDS) is a popular method, which is necessary to compute the distance matrix. The Unifrac distance is very reasonable and biologically meaningful in the analysis of microbiome data. Due to the complexity of the phylogenetic tree and the high dimensionality of data, MDS needs a large amount of calculations to determine all the distances between pairs. In this paper, we proposed a novel di...

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