National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21472056, 21602070, 21672182]
机构署名：
本校为通讯机构
院系归属：
化学学院
摘要：
A fascinating new form of the Hantzsch reaction with methyl ketones and pyrazol-5-amines for the selective synthesis of dipyrazolo-fused pyridines has been discovered. This special [3 + 2 + 1] heteroannulation was accomplished via the domino generation of two C-C bonds and one C-N bond. Preliminary mechanistic studies indicated that the I2/DMSO system realized the oxidative carbonylation of Csp3-H of methyl ketones, while Cu(OTf)2 acted as a relay reagent to a...
