7-Benzyl-5,6,7,8-tetrahydropyrido[4 ' ,3 ' :4,5]thieno[2,3-d] pyrimidin-4(3 H)-ones were synthesized by base catalyzed reactions of nucleophilic reagents (aliphatic amines, alcohols or phenols) with carbodiimides 4 , which in turn were obtained by the aza-Wittig reaction of iminophosphoranes 3 with aromatic isocyanates. 20...