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Construction and bioimaging application of novel indole heptamethine cyanines containing functionalized tetrahydropyridine rings

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成果类型:
期刊论文
作者:
Ma, Xiaoxie;Zhang, Chen;Feng, Lan;Liu, Sheng Hua;Tan, Ying*;...
通讯作者:
Yin, Jun;Tan, Ying
作者机构:
[Liu, Sheng Hua; Feng, Lan; Yin, Jun; Ma, Xiaoxie] Cent China Normal Univ, Hubei Int Sci & Technol Cooperat Base Pesticide &, Int Joint Res Ctr Intelligent Biosensing Technol, Coll Chem,Minist Educ,Key Lab Pesticide & Chem Bi, Wuhan 430079, Peoples R China.
[Zhang, Chen; Tan, Ying] Tsinghua Univ, Grad Sch Shenzhen, State Key Lab Chem Oncogen, Key Lab Chem Biol, Shenzhen 518055, Peoples R China.
通讯机构:
[Yin, Jun] C
[Tan, Ying] T
Cent China Normal Univ, Hubei Int Sci & Technol Cooperat Base Pesticide &, Int Joint Res Ctr Intelligent Biosensing Technol, Coll Chem,Minist Educ,Key Lab Pesticide & Chem Bi, Wuhan 430079, Peoples R China.
Tsinghua Univ, Grad Sch Shenzhen, State Key Lab Chem Oncogen, Key Lab Chem Biol, Shenzhen 518055, Peoples R China.
语种:
英文
期刊:
JOURNAL OF MATERIALS CHEMISTRY B
ISSN:
2050-750X
年:
2020
卷:
8
期:
43
页码:
9906-9912
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21676113, 21772054]; Distinguished Young Scholar of Hubei Province [2018CFA079]; 111 ProjectMinistry of Education, China - 111 Project [B17019]; Scholar support program of CCNU [0900-31101090002]; excellent doctorial dissertation cultivation grant of CCNU from the colleges' basic research and operation of MOE [2019YBZZ029]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
IR780 as a commercially available dye with near-infrared emission has been extensively applied in fluorescent probes and bioimaging. In this work, to further intensify the optical behavior, a tetrahydropyridine ring was used to replace the cyclohexene ring at the center of IR780, forming a cyanine dye Cy-NH with near-infrared emission. Photophysical properties demonstrated that Cy-NH exhibits good optical performance. In particular, Cy-NH contains two functional reaction sites (e.g. Cl and NH sites on the tetrahydropyridine ring) and can be used to construct functional cyanine dyes. Investigat...

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