Conceptualization, A.X., Z.Y. and P.H.; methodology, A.X., D.S. and Z.Y.; validation, A.X., P.C. and Z.L.; formal analysis, D.S., Z.L. and Q.T.; investigation, D.L., X.Z., J.L. and Y.J.; data curation, A.X. and Z.Y.; writing—original draft preparation, A.X. and Z.Y.; writing—review and editing, Z.Y. and P.H.; supervision, Z.Y. and P.H.; project administration, Z.Y. and P.H.; funding acquisition, P.H. All authors have read and agreed to the published version of the manuscript. This research received no external funding.