期刊论文

Application of Propargylic Radicals in Organic Synthesis

Lu Liang-Qiu;Xiao Wen-Jing

中文

化学学报

0567-7351

2019

77

9

803-813

10.6023/A19060201

* E-mail: luliangqiu@mail.ccnu.edu.cn; wxiao@mail.ccnu.edu.cn Received June 8, 2019; published August 13, 2019. Project supported by the National Natural Science Foundation of China (Nos. 21572074, 21772052 and 21772053) and the Natural Science Foundation of Hubei Province (Nos. 2015CFA033, 2017AHB047). 项目受国家自然科学基金(Nos. 21572074, 21772052, 21772053)和湖北省自然科学基金(Nos. 2015CFA033, 2017AHB047)资助.

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The production and transformation of alkynes occupys an important position in organic synthetic chemistry. Within this realm, propargylic functionalization of alkynes is a feasible way towards this purpose. Especially, the propargylic functionalization via radical pathways has flourished in the last decade, which is believed to be a significant complement to the classic metal-catalyzed propargylation reaction involving cationic intermediates. According to the reaction modes, these advancements will be highlighted by classifying into four types. The first one is the propargylic functionalizatio...