期刊论文

Cheng, Ying;Lu, Liang-Qiu

英文

中国化学

1001-604X

2020

38

12

1671-1675

10.1002/cjoc.202000309

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21901080, 21822103, 21820102003, 91956201]; Program of Introducing Talents of Discipline to Universities of China (111 Program) [B17019]; Natural Science Foundation of Hubei ProvinceNatural Science Foundation of Hubei Province [2017AHB047]; International Joint Research Center for Intelligent Biosensing Technology and Health

本校为第一且通讯机构

Summary of main observation and conclusionAn enantioselective deoxygenative cyanation of benzyl alcohols was accomplished for the first time through the synergistic photoredox and copper catalysis. This reaction features the use of organic photosensitizer and low‐cost 3d metal catalyst, simple and safe operations, and extremely mild conditions. A variety of chiral benzyl nitriles were produced in generally good yields and high level of enantiocontrols from readily available feedstocks (22 examples, up to 93% yield and 92% ee...