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pH-Stimulated Response Gating for Mimic Cytochrome C Transport on Biomimetic Asymmetric Nanochannels

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成果类型:
期刊论文
作者:
Yang, Qinglin;Li, Guang;Xu, Weiwei;Qu, Haonan;Hameed, Muhammad Salman;...
通讯作者:
Li, HB;Quan, JX;Zhang, J;Sun, ZY
作者机构:
[Li, Guang; Xu, Weiwei; Hameed, Muhammad Salman; Yang, Qinglin; Li, Haibing; Qu, Haonan] Cent China Normal Univ, Coll Chem, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China.
[Quan, Jiaxin; Quan, JX] Hanjiang Normal Univ, Dept Chem Biol & Environm Engn, Shiyan 442000, Peoples R China.
[Zhang, J; Zhang, Jin] Yunnan Normal Univ, Coll Chem & Chem Engn, Kunming 650092, Peoples R China.
[Sun, Zhongyue] Hubei Univ Chinese Med, Sch Lab Med, Wuhan 430065, Peoples R China.
通讯机构:
[Quan, JX ; Sun, ZY ] H
[Li, HB ] C
[Zhang, J ] Y
Cent China Normal Univ, Coll Chem, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China.
Hanjiang Normal Univ, Dept Chem Biol & Environm Engn, Shiyan 442000, Peoples R China.
语种:
英文
关键词:
arginine;biomimetic;mimic Cyt C transport;nanochannel;pH
期刊:
ACS Applied Materials & Interfaces
ISSN:
1944-8244
年:
2024
卷:
16
期:
5
页码:
6284-6289
基金类别:
National Key Research and Development Program [2021YFA0716702]; National Natural Science Foundation of China [22371086, 22071074]; The 111 Project [B17019]; Self-determined research funds of CCNU from the colleges'basic research and operation of MOE
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
Proteins are vital components in cells, biological tissues, and organs, playing a pivotal role in growth and developmental processes in living organisms. Cytochrome C (Cyt C) is a class of heme proteins found in almost all life and is involved in cellular energy metabolic processes such as respiration, mainly as electron carriers or terminal reductases. It binds cardiolipin in the inner mitochondrial membrane, leading to apoptosis. It is a challenge to design a simple and effective artificial system to mimic the complex Cyt C biological transport process. In this paper, an asymmetric biomimeti...

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