National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [61532008, 31371275]; CCNU from the Colleges' Basic Research and Operation of MOEMinistry of Education, Singapore [CCNU17TS0003]
机构署名:
本校为第一且通讯机构
院系归属:
计算机学院
摘要:
Gene (microRNA) identification is a key step in understanding the cellular mechanisms. Compared with biological experiments, computational prediction of disease genes is cheaper and more effortless. In this study, we analyzed the properties of tumor-associated microRNA in mouse and found that tumor-associated genes display 8distinguishingfeatures when compared with genes not yet known to be involved in tumor. The features of tumor-associated genes tend to located at network center and interact with each other were found by analyze the network characteristics. In addition, the features of the t...