When near-infrared fluorescence meets supramolecular coordination complexes: Challenges and opportunities of metallacycles/metallacages in precision biomedicine

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成果类型：

期刊论文

作者：

Xu, Yuling;Dou, You;Li, Qian;Ye, Huan;Li, Yuntao;...

通讯作者：

Qiu, S;Li, Junrong;Sun, Y;Xiong, XX

作者机构：

[Xu, Yuling; Qiu, Sheng; Li, Yuntao] Zhejiang Univ, Huzhou Cent Hosp, Affiliated Huzhou Hosp, Dept Neurosurg,Sch Med, Huzhou 313000, Peoples R China.

[Xu, Yuling; Ye, Huan; Dou, You; Sun, Y; Li, Junrong; Sun, Yao; Li, Qian; Li, JR] Cent China Normal Univ, Coll Chem, Natl Key Lab Green Pesticides, Wuhan 430079, Peoples R China.

[Xiong, Xiaoxing; Li, Qian] Wuhan Univ, Dept Neurosurg, Renmin Hosp, Wuhan 430060, Peoples R China.

[Ye, Huan] Hubei Prov Key Lab Mol Imaging, Wuhan 430022, Peoples R China.

[Sun, Yao; Li, Yuntao] Qingdao Univ Sci & Technol, Key Lab Opt Elect Sensing & Analyt Chem Life Sci, Minist Educ, Qingdao 266061, Peoples R China.

通讯机构：

[Qiu, S ] Z

[Li, JR; Sun, Y ] C

[Xiong, XX ] W

Zhejiang Univ, Huzhou Cent Hosp, Affiliated Huzhou Hosp, Dept Neurosurg,Sch Med, Huzhou 313000, Peoples R China.

Cent China Normal Univ, Coll Chem, Natl Key Lab Green Pesticides, Wuhan 430079, Peoples R China.

语种：

英文

关键词：

Metallacycles;metallacages;Near-infrared biochannel;In vivo imaging;Theranostic

期刊：

Coordination Chemistry Reviews

ISSN：

0010-8545

年：

2023

卷：

493

页码：

215320

DOI：

10.1016/j.ccr.2023.215320

基金类别：

National Key Research and Development Program [2021YFA0716702]; National Natural Science Foundation of China [22022404, 22074050]; National Natural Science Foundation of Hubei Province (China) [2022CFA033]; Fundamental Research Funds for the Central Universities [CCNU22QN007]; Hubei Province Key Laboratory of Molecular Imaging [2022fzyx028]; Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE [M2022-6]

机构署名：

本校为通讯机构

院系归属：

化学学院

摘要：

In the past decade, the metallacycles/metallacages have attracted unremitting interest in biomedical fields, yet visual tracking of their in vivo delivery, targeting ability, biodistribution and therapeutic evaluation are still hampered by their short emission wavelengths. More recently, the near-infrared biochannel (NIR, 0.7-1.7 & mu;m) especially the NIR-II region (1.0-1.7 & mu;m) provides deeper tissue penetration and higher contrast than traditional UV-Vis region for in vivo imaging. In this context, we provide a comprehensive and systematic insight into the development of NIR metallacycle...

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When near-infrared fluorescence meets supramolecular coordination complexes: Challenges and opportunities of metallacycles/metallacages in precision biomedicine

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