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Small RNA analysis provides new insights into cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia

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成果类型:
期刊论文
作者:
Zheng, Ya;Shen, Wei;Bi, Jie;Chen, Meng-Yan;Wang, Rui-Fang;...
通讯作者:
Wang, Yu-Feng
作者机构:
[Bi, Jie; Chen, Meng-Yan; Shen, Wei; Ai, Hui; Zheng, Ya; Wang, Rui-Fang; Wang, Yu-Feng] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Wang, Yu-Feng] C
Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Hubei, Peoples R China.
语种:
英文
关键词:
Cytoplasmic incompatibility;Drosophila melanogaster;MicroRNA;Pipsqueak;Wolbachia
期刊:
Journal of Insect Physiology
ISSN:
0022-1910
年:
2019
卷:
118
页码:
103938
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31501893, 31672352]
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
摘要:
Wolbachia is a genus of endosymbiotic bacteria that induce a wide range of effects on their insect hosts. Cytoplasmic incompatibility (CI) is the most common phenotype mediated by Wolbachia and results in embryonic lethality when Wolbachia-infected males mate with uninfected females. Studies have revealed that bacteria can regulate many cellular processes in their hosts using small non-coding RNAs, so we investigated the involvement of small RNAs (sRNAs) in CI. Comparison of sRNA libraries between Wolbachia-infected and uninfected Drosophila melanogaster testes revealed 18 novel microRNAs (miR...

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