The matrix effect is a problem of much concern in U-Pb isotopic dating by in situ LA-ICP-MS,and its influence on the accuracy of the dating results should not be ignored. The authors intend to study the influences and correction methods of matrix effects on U-Pb isotopic dating by in-situ LA-ICP-MS for such minerals as baddeleyite, rutile, cassiterite, columbite, uraninite, pitchblende and other oxide-type U-bearing minerals. This paper briefly describes the advantages and limitations of these correction methods in the hope of finding some regu...