期刊论文

Rui Li<&wdkj&>Xu Yang

英文

生物学前沿

1674-7984

2013

8

4

444-450

10.1007/s11515-013-1266-y

This work was supported by the grants of the National Natural Science Foundation of China (Grant No. 21103059) and the Innovative Experiment Program for University Students of Chinese Ministry of Education.

本校为第一且通讯机构

To compare the cytotoxicity on HeLa cells induced by nanosized and microsized tellurium powders, HeLa cells were exposed to different concentrations of tellurium powders (0, 50, 100, 150 and 200 μg/mL) for 12 h. In this study, detection of a series of biomarkers, including reactive oxygen species (ROS), glutathione (GSH), 8-hydroxy-2′-deoxyguanosine (8-OHdG), in addition to DNA and protein crosslink (DPC) and MTTassay, were conducted to evaluate the cytotoxicity. It is indicated that compared with the control group, there was no significant d...

为了在 HeLa 房间上比较 cytotoxicity，由 nanosized 和 microsized 碲粉末导致了， HeLa 房间为 12 h 暴露于碲粉末(0， 50， 100， 150 和 200 g/mL ) 的不同集中。在这研究，一系列 biomarkers 的察觉包括反应的氧种类(ROS ) ，谷胱甘肽(GSH ) ，除了 DNA 和蛋白质交叉连接(DPC ) 和 MTTassay， 8-hydroxy-2-deoxyguanosine (8-OHdG ) 被进行评估 cytotoxicity。与控制组相比，在在比为 nanosized 和 microsized 碲粉末的 50 g/mL 低的集中的导致的 cytotoxicity 没有重要差别，这被显示。当出现时，当集中比 100 g/mL 以及为 microsized 碲粉末高时，当集中比 200 g/mL 高时，在为 nanosiz...