期刊论文

Yang, Guangfu;Sun, Yao

英文

Advanced Healthcare Materials

2192-2640

2018

7

23

1800973-

10.1002/adhm.201800973

F.D., C.L., and Y.X. contributed equally to this work. This work was supported by grants from the National Key R&D Program (2017YFA0505203), NSFC (21708012, 21772055), NSFHP (2017CFB151), and the financial support by self-determined research funds of CCNU from the colleges, basic research and operation of MOE (23020205170469), 111 projectB17019, and the Open Research Fund of State Key Laboratory of Analytical Chemistry for Life Science (SKLACLS1815). Thanks to Suzhou NIR-Optics Technologies Co., Ltd (Suzhou, China). Without their technical help, this project could not process smoothly.

本校为第一且通讯机构

To date, small-molecule dye–based probes have been at the forefront of research in biomedical imaging, especially in the second near-infrared (NIR-II) window (1.0–1.7 µm). However, how to precisely regulate the synthesized size of NIR-II organic dye–based probes remains challenging. Moreover, systematic studies on whether the size of NIR-II probes affects optical/pharmacokinetic properties are still rare. Here, an ingenious PEGylation strategy is developed to regulate the self-assembly size of organic dye–based (CH1055 scaffold) NIR-II pro...