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Efficient approach to 2-hydroxy-2,3-dihydrofuran derivatives and its application for the synthesis of novel 4-(1H-pyrazol-4-yl)pyridazines

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成果类型:
期刊论文
作者:
Ma, Jun-Rui;Shu, Wen-Ming;Zheng, Kai-Lu;Ni, Fan;Yin, Guo-Dong*;...
通讯作者:
Yin, Guo-Dong
作者机构:
[Wu, An-Xin; Ma, Jun-Rui; Ni, Fan; Zheng, Kai-Lu; Shu, Wen-Ming] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.
[Yin, Guo-Dong] Hubei Normal Univ, Hubei Collaborat Innovat Ctr Rare Met Chem, Hubei Key Lab Pollutant Anal & Reuse Technol, Huangshi 435002, Peoples R China.
通讯机构:
[Yin, Guo-Dong] H
Hubei Normal Univ, Hubei Collaborat Innovat Ctr Rare Met Chem, Hubei Key Lab Pollutant Anal & Reuse Technol, Huangshi 435002, Peoples R China.
语种:
英文
期刊:
Organic & Biomolecular Chemistry
ISSN:
1477-0520
年:
2015
卷:
13
期:
17
页码:
4976-4980
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21272085, 21472056]; Educational Commission of Hubei Province [D20142501]
机构署名:
本校为第一机构
院系归属:
化学学院
摘要:
A highly efficient method for the synthesis of 2-hydroxy-2,3-dihydrofuran derivatives from 1,4-enediones and phenacyl pyridinium halides via a domino reaction has been developed. This is a simple and beneficial strategy for the construction of 2-hydroxy-2,3-dihydrofuran compounds from readily available starting materials under mild conditions. Moreover, the application of this reaction provides a straightforward and practical route for the sy...

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