This paper makes use of the relevant theories of transnational corporations(TNCs) to have in-depth analysis on the layout and strategy of TNCs' global operating and global management, and farther probe into the changes and trends in the organizational structure and business model of TNCs. The paper points out that: the imperfectness of international market brings about transaction costs, but also provides opportunities for earning profits. The enterprises bear the transaction costs in order to achieve the expansion of trade and profit. The organization will select the operating method with hig...