To explore protein oxidative damage induced by gaseous formaldehyde and its mechanism we carried out this study. Mice were treated with gaseous formaldehyde at different levels (0 mg.m(-3) 0.68 mg.m(-3) and 3.0 mg.m(-3)) for 72 hr and the protein carbonyl content was mensurated using spectrophotometric DNPH assay to reflect the degree of protein oxidative damage. The results show that the protein carbonyl content of brain, heart and liver tissue in mice decrease in the group of 0.68 mg.m(-3) (p < 0.01, p < 0.01, p < 0.05), while increase significantly in heart and liver tissue in the group of ...
