In the universality class of the critical point of QCD, the appearance of the inflection point in the equation of state (EoS) is associated with the second order phase transition. The high cumulants of conserved quantities near the critical point are corresponding to the high derivatives of the EoS near the inflection point. The critical behavior of high cumulants of conserved charge near the QCD critical point, in particular, the sign change, is closely related to the appearance of inflection point. We show in general how the times of sign change of high cumulants relate to the order of deriv...