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Coumarin-based novel fluorescent zinc ion probe in aqueous solution

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成果类型:
期刊论文
作者:
Li, Jun;Zhang, Chun-Fang;Ming, Ze-Zhong;Hao, Ge-Fei;Yang, Wen-Chao*;...
通讯作者:
Yang, Wen-Chao
作者机构:
[Yang, Guang-Fu; Li, Jun; Yang, Wen-Chao; Zhang, Chun-Fang; Ming, Ze-Zhong; Hao, Ge-Fei] Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
通讯机构:
[Yang, Wen-Chao] C
Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Coumarin;Zn2+;Fluorescent probe
期刊:
Tetrahedron
ISSN:
0040-4020
年:
2013
卷:
69
期:
23
页码:
4743-4748
基金类别:
National Basic Research Program of ChinaNational Basic Research Program of China [2010CB126103]; NSFCNational Natural Science Foundation of China (NSFC) [20925206, 21172091, 21102052]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
A novel coumarin-derived fluorescent probe, FCP, was designed for Zn2+ quantification based on the photo-induced electron transfer (PET) mechanism. This probe selectively and sensitively detects Zn2+ in aqueous solution with wide pH range. Large fluorescence enhancement (13-fold) was observed upon the addition of Zn2+. FCP also displays excellent cell permeability in HeLa cell model and very low cytotoxicity to HEK-293 cell ...

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