Microprotein Dysregulation in the Serum of Patients with Atrial Fibrillation

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhang, Zheng;Tian, Tao;Pan, Ni;Wang, Yi;Peng, Mingbo;...

通讯作者：

Cuihong Wan

作者机构：

[Wang, Yi; Wan, Cuihong; Zhang, Zheng; Peng, Mingbo; Pan, Ni] Cent China Normal Univ, Sch Life Sci, Wuhan 430079, Hubei, Peoples R China.

[Wang, Yi; Wan, Cuihong; Zhang, Zheng; Peng, Mingbo; Pan, Ni] Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Hubei, Peoples R China.

[Tian, Tao; Pan, Zhenwei; Zhao, Xinbo] Minist Educ, Dept Pharmacol, Key Lab Cardiovasc Med Res, Harbin 150081, Heilongjiang, Peoples R China.

[Tian, Tao; Pan, Zhenwei; Zhao, Xinbo] Harbin Med Univ, State Prov Key Labs Biomed Pharmaceut China, Harbin 150081, Heilongjiang, Peoples R China.

通讯机构：

[Cuihong Wan] S

School of Life Sciences and Hubei Key Laboratory of Genetic Regulation and Integrative Biology, Central China Normal University, Wuhan, Hubei 430079, People’s Republic of China

语种：

英文

关键词：

APCO1;LC/MS/MS;atrial fibrillation;cardiac homeostasis;machine learning;microproteins;serum proteomics

期刊：

JOURNAL OF PROTEOME RESEARCH

ISSN：

1535-3893

年：

2023

卷：

期：

页码：

1172-1180

DOI：

10.1021/acs.jproteome.2c00622

基金类别：

Natural Science Foundation of China [31800647]; basic research and operation of MOE [CCNU19TD007]

机构署名：

本校为第一机构

院系归属：

生命科学学院

摘要：

The incidence rate of atrial fibrillation (AF) has stayed at a high level in recent years. Despite the intensive efforts to study the pathologic changes of AF, the molecular mechanism of disease development remains unclarified. Microproteins are ribosomally translated gene products from small open reading frames (sORFs) and are found to play crucial biological functions, while remain rare attention and indistinct in AF study. In this work, we recruited 65 AF patients and 65 healthy subjects for microproteomic profiling. By differential analysis and cross-validation between independent datasets...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Microprotein Dysregulation in the Serum of Patients with Atrial Fibrillation

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问